Title : Improved insulin sensitivity and islet function after PPARdelta activation in diabetic db/db mice.

Pub. Date : 2010 Jan 25

PMID : 19818749






3 Functional Relationships(s)
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1 Whether PPARdelta is involved in the regulation of glucose metabolism is not completely understood. Glucose peroxisome proliferator activator receptor delta Mus musculus
2 Following intravenous glucose (1g/kg), glucose tolerance was improved after PPARdelta activation (K(G) 1.3+/-0.6 vs. -0.05+/-0.7 %/min, P=0.048). Glucose peroxisome proliferator activator receptor delta Mus musculus
3 This suggests that activation of PPARdelta improves glucose metabolism and may therefore potentially be target for treatment of type 2 diabetes. Glucose peroxisome proliferator activator receptor delta Mus musculus