Title : Demethoxycurcumin suppresses migration and invasion of MDA-MB-231 human breast cancer cell line.

Pub. Date : 2010 Feb 10

PMID : 19818349






2 Functional Relationships(s)
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1 MDA-MB-231 cells treated with DMC had decreased levels of ECM degradation-associated proteins including matrix metalloproteinase-9 (MMP-9), membrane type-1 matrix metalloproteinase (MT1-MMP), urokinase plasminogen activator (uPA) and uPA receptor (uPAR), while the level of uPA inhibitor (PAI-1) was up-regulated. demethoxycurcumin matrix metallopeptidase 9 Homo sapiens
2 MDA-MB-231 cells treated with DMC had decreased levels of ECM degradation-associated proteins including matrix metalloproteinase-9 (MMP-9), membrane type-1 matrix metalloproteinase (MT1-MMP), urokinase plasminogen activator (uPA) and uPA receptor (uPAR), while the level of uPA inhibitor (PAI-1) was up-regulated. demethoxycurcumin matrix metallopeptidase 9 Homo sapiens