Title : Antimicrobial activity of human prion protein is mediated by its N-terminal region.

Pub. Date : 2009 Oct 7

PMID : 19809501






1 Functional Relationships(s)
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1 CONCLUSIONS: The demonstration of an antimicrobial activity of PrP, localisation of its activity to the N-terminal and heparin-binding region, combined with results showing an increased expression of PrP during wounding, indicate that PrPs could have a previously undisclosed role in host defense. Heparin prion protein Homo sapiens