Pub. Date : 2009 Oct 15
PMID : 19808956
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | We also found that arsenite-induced phosphorylation of extracellular signal-regulated kinases (ERK) or c-Jun NH(2)-terminal kinases (JNK) was markedly suppressed by Tpl2 kinase inhibitor or Tpl2 short hairpin RNA. | arsenite | mitogen-activated protein kinase 8 | Homo sapiens |
| 2 | We also found that arsenite-induced phosphorylation of extracellular signal-regulated kinases (ERK) or c-Jun NH(2)-terminal kinases (JNK) was markedly suppressed by Tpl2 kinase inhibitor or Tpl2 short hairpin RNA. | arsenite | mitogen-activated protein kinase 8 | Homo sapiens |
| 3 | Inhibition of arsenite-induced ERK or JNK signaling using a pharmacologic inhibitor of ERK or JNK substantially blocked COX-2 expression. | arsenite | mitogen-activated protein kinase 8 | Homo sapiens |
| 4 | Inhibition of arsenite-induced ERK or JNK signaling using a pharmacologic inhibitor of ERK or JNK substantially blocked COX-2 expression. | arsenite | mitogen-activated protein kinase 8 | Homo sapiens |
| 5 | Our results show that Tpl2 plays a key role in arsenite-induced COX-2 expression and PGE(2) production and further elucidate the role of Tpl2 in arsenite signals that activate ERK/JNK and NF-kappaB/AP-1 in JB6 P+ cells. | arsenite | mitogen-activated protein kinase 8 | Homo sapiens |
| 6 | Our results show that Tpl2 plays a key role in arsenite-induced COX-2 expression and PGE(2) production and further elucidate the role of Tpl2 in arsenite signals that activate ERK/JNK and NF-kappaB/AP-1 in JB6 P+ cells. | arsenite | mitogen-activated protein kinase 8 | Homo sapiens |