Pub. Date : 2009 Oct 6
PMID : 19806194
9 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The proteins encoded by the two Nv-NF-kappaB alleles have different molecular properties, in part due to a Cys/Ser polymorphism at residue 67, which resides within the DNA recognition loop. | Cysteine | nuclear factor kappa B subunit 1 | Homo sapiens |
| 2 | In nearly all previously characterized NF-kappaB proteins, the analogous residue is fixed for Cys, and conversion of human RHD proteins from Cys to Ser at this site has been shown to increase DNA-binding ability and increase resistance to inhibition by thiol-reactive compounds. | Cysteine | nuclear factor kappa B subunit 1 | Homo sapiens |
| 3 | In nearly all previously characterized NF-kappaB proteins, the analogous residue is fixed for Cys, and conversion of human RHD proteins from Cys to Ser at this site has been shown to increase DNA-binding ability and increase resistance to inhibition by thiol-reactive compounds. | Cysteine | nuclear factor kappa B subunit 1 | Homo sapiens |
| 4 | Reciprocal Cys<->Ser mutations at residue 67 of the native Nv-NF-kappaB proteins affect DNA binding as in human NF-kappaB proteins, e.g., a Cys->Ser mutation increases DNA binding of the native Cys variant. | Cysteine | nuclear factor kappa B subunit 1 | Homo sapiens |
| 5 | Reciprocal Cys<->Ser mutations at residue 67 of the native Nv-NF-kappaB proteins affect DNA binding as in human NF-kappaB proteins, e.g., a Cys->Ser mutation increases DNA binding of the native Cys variant. | Cysteine | nuclear factor kappa B subunit 1 | Homo sapiens |
| 6 | Reciprocal Cys<->Ser mutations at residue 67 of the native Nv-NF-kappaB proteins affect DNA binding as in human NF-kappaB proteins, e.g., a Cys->Ser mutation increases DNA binding of the native Cys variant. | Cysteine | nuclear factor kappa B subunit 1 | Homo sapiens |
| 7 | Reciprocal Cys<->Ser mutations at residue 67 of the native Nv-NF-kappaB proteins affect DNA binding as in human NF-kappaB proteins, e.g., a Cys->Ser mutation increases DNA binding of the native Cys variant. | Cysteine | nuclear factor kappa B subunit 1 | Homo sapiens |
| 8 | Reciprocal Cys<->Ser mutations at residue 67 of the native Nv-NF-kappaB proteins affect DNA binding as in human NF-kappaB proteins, e.g., a Cys->Ser mutation increases DNA binding of the native Cys variant. | Cysteine | nuclear factor kappa B subunit 1 | Homo sapiens |
| 9 | Reciprocal Cys<->Ser mutations at residue 67 of the native Nv-NF-kappaB proteins affect DNA binding as in human NF-kappaB proteins, e.g., a Cys->Ser mutation increases DNA binding of the native Cys variant. | Cysteine | nuclear factor kappa B subunit 1 | Homo sapiens |