Title : Adrenergic beta(2)-receptor genotype predisposes to exacerbations in steroid-treated asthmatic patients taking frequent albuterol or salmeterol.

Pub. Date : 2009 Dec

PMID : 19800676






2 Functional Relationships(s)
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1 We have shown that the Arg16 allele of the adrenergic beta(2)-receptor agonist gene (ADRB2) predisposes to exacerbations in young asthmatic patients taking regular salmeterol. Salmeterol Xinafoate adrenoceptor beta 2 Homo sapiens
2 CONCLUSION: The Arg16 genotype of ADRB2 is associated with exacerbations in asthmatic children and young adults exposed daily to beta(2)-agonists, regardless of whether the exposure is to albuterol or long-acting agonists, such as salmeterol. Salmeterol Xinafoate adrenoceptor beta 2 Homo sapiens