Title : Osteolytic prostate cancer cells induce the expression of specific cytokines in bone-forming osteoblasts through a Stat3/5-dependent mechanism.

Pub. Date : 2010 Feb

PMID : 19796718






1 Functional Relationships(s)
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1 Most importantly, the induction of Cxcl5, Cxcl12 and Tnfsf11 in osteoblasts by PC-3-conditioned medium was abrogated by the Stat3/5 inhibitor piceatannol, whereas the selective blockade of Stat1 and Erk activation had no effect. 3,3',4,5'-tetrahydroxystilbene mitogen-activated protein kinase 1 Homo sapiens