Pub. Date : 2010 Mar-Apr
PMID : 19770794
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Switching from atorvastatin to simvastatin in patients at high cardiovascular risk: effects on low-density lipoprotein cholesterol. | Simvastatin | component of oligomeric golgi complex 2 | Homo sapiens |
2 | We examined the association between switching from atorvastatin to simvastatin and changes in low-density lipoprotein cholesterol (LDL-C) levels in clinical practice. | Simvastatin | component of oligomeric golgi complex 2 | Homo sapiens |
3 | We examined the association between switching from atorvastatin to simvastatin and changes in low-density lipoprotein cholesterol (LDL-C) levels in clinical practice. | Simvastatin | component of oligomeric golgi complex 2 | Homo sapiens |
4 | Switched patients who were not prescribed a higher milligram dose of simvastatin were significantly less likely to reach an LDL-C less than 100 mg/dL (62.3% versus 74.0%; odds ratio, 0.55; 95% confidence interval, 0.36-0.84; P = 0.006) and had higher LDL-C (95.1 versus 87.2 mg/dL; P = 0.002) than control subjects. | Simvastatin | component of oligomeric golgi complex 2 | Homo sapiens |
5 | A large proportion of patients who switch from atorvastatin to simvastatin are prescribed doses that are not therapeutically equivalent, and these patients were significantly less likely to meet LDL-C treatment goals compared with patients who remained on atorvastatin. | Simvastatin | component of oligomeric golgi complex 2 | Homo sapiens |