Pub. Date : 2009 Nov-Dec
PMID : 19759279
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Exposure to 20 microM caffeine during EWD produced cytotoxicity in all hippocampal regions, though toxicity was sex-dependent in the DG and CA1 region. | Caffeine | carbonic anhydrase 1 | Rattus norvegicus |
| 2 | Similarly, 20 microM caffeine caused markedly greater toxicity in female cultures as compared to male cultures in the CA1 region. | Caffeine | carbonic anhydrase 1 | Rattus norvegicus |
| 3 | CONCLUSIONS: Twenty-four-hour exposure to caffeine during EWD produced significant toxicity in the pyramidal cell layer of the CA3 region in male and female cultures, though toxicity in the granule cell layer of the DG and pyramidal cell layer of the CA1 region was observed only in female cultures. | Caffeine | carbonic anhydrase 1 | Rattus norvegicus |