Title : PH domain leucine-rich repeat protein phosphatase 1 contributes to maintain the activation of the PI3K/Akt pro-survival pathway in Huntington's disease striatum.

Pub. Date : 2010 Feb

PMID : 19745829






1 Functional Relationships(s)
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1 The analysis of the conditional mouse model Tet/HD94 disclosed that after mutant huntingtin shutdown PHLPP1 levels returned to wild-type levels whereas phospho-Akt levels were partially reduced. tetramethylenedisulfotetramine huntingtin Mus musculus