Title : Inhibition of anti-IgE induced skin response in normals by formoterol, a new beta 2-adrenoceptor agonist, and terbutaline. 1. Dose response relation and duration of effect on the early wheal and flare response.

Pub. Date : 1990 Jul

PMID : 1974124






3 Functional Relationships(s)
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1 Inhibition of anti-IgE induced skin response in normals by formoterol, a new beta 2-adrenoceptor agonist, and terbutaline. Terbutaline immunoglobulin heavy constant epsilon Homo sapiens
2 The intention of the present study was to compare formoterol and terbutaline regarding ability to inhibit immediate wheal and flare responses (WFR) to anti-human IgE with focus on the duration of anti-WFR action. Terbutaline immunoglobulin heavy constant epsilon Homo sapiens
3 The drugs injected intradermally 2 min prior to challenge with anti-IgE in volunteers produced a dose-dependent inhibition of the WFR in the range 1pg-100ng (formoterol) and 1ng-1 microgram (terbutaline). Terbutaline immunoglobulin heavy constant epsilon Homo sapiens