Pub. Date : 2009 Nov
PMID : 19734018
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | We previously showed that histamine enhanced transcriptional activity of activator protein-1 (AP-1) in human keratinocytes by inducing the expression of AP-1 component c-Fos via the activation of extracellular signal-regulated kinase (ERK) through H1 receptors. | Histamine | mitogen-activated protein kinase 1 | Homo sapiens |
| 2 | We previously showed that histamine enhanced transcriptional activity of activator protein-1 (AP-1) in human keratinocytes by inducing the expression of AP-1 component c-Fos via the activation of extracellular signal-regulated kinase (ERK) through H1 receptors. | Histamine | mitogen-activated protein kinase 1 | Homo sapiens |
| 3 | CONCLUSION: It is suggested that histamine induces hBD-3 production in human keratinocytes through H1 receptors by activating STAT3 and AP-1 via JAK2 and MEK/ERK. | Histamine | mitogen-activated protein kinase 1 | Homo sapiens |