Title : Sumoylated PPARalpha mediates sex-specific gene repression and protects the liver from estrogen-induced toxicity in mice.

Pub. Date : 2009 Oct

PMID : 19729835






1 Functional Relationships(s)
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1 Here we show that in mice, PPARalpha has broad female-dependent repressive actions on hepatic genes involved in steroid metabolism and immunity. Steroids peroxisome proliferator activated receptor alpha Mus musculus