Title : CpG-containing immunostimulatory DNA sequences elicit TNF-alpha-dependent toxicity in rodents but not in humans.

Pub. Date : 2009 Sep

PMID : 19726873






1 Functional Relationships(s)
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1 Knockout mouse experiments demonstrated that ISS-induced toxicity was critically dependent on TNF-alpha, with IFN-alpha required for TNF-alpha induction. ISS tumor necrosis factor Mus musculus