Title : Rational design and synthesis of highly potent anti-acetylcholinesterase activity huperzine A derivatives.

Pub. Date : 2009 Oct 1

PMID : 19726199






1 Functional Relationships(s)
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1 In the docking model, we confirmed that aromatic ring of Hup A derivatives played the pi-pi stacking against aminophenol residues of AChE, and the structure-activity relationship (SAR) was discussed. Aminophenols acetylcholinesterase (Cartwright blood group) Homo sapiens