Title : Ginsenoside Rd prevents glutamate-induced apoptosis in rat cortical neurons.

Pub. Date : 2010 Feb

PMID : 19719747






2 Functional Relationships(s)
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1 Ginsenoside Rd (1, 3 and 10 micromol/L) concentration-dependently inhibited caspase 3 activation and expression of the p20 subunit of active caspase 3 (by 30 +/- 10%, 41 +/- 9% and 62 +/- 19%, respectively, compared with glutamate alone; P < 0.05), whereas 1 micromol/L nimodipine had no effect. Ginsenosides caspase 3 Rattus norvegicus
2 Ginsenoside Rd (1, 3 and 10 micromol/L) concentration-dependently inhibited caspase 3 activation and expression of the p20 subunit of active caspase 3 (by 30 +/- 10%, 41 +/- 9% and 62 +/- 19%, respectively, compared with glutamate alone; P < 0.05), whereas 1 micromol/L nimodipine had no effect. Ginsenosides caspase 3 Rattus norvegicus