Title : Role of P2 glycine in determining the specificity of antithrombin reaction with coagulation proteases.

Pub. Date : 2009 Nov 6

PMID : 19715676






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 AT with a P2-Phe inhibited thrombin with >150-fold impaired reactivity, however, the defect was restored by either pentasaccharide or by replacing Leu-99 of thrombin with a Gly. Phenylalanine coagulation factor II, thrombin Homo sapiens
2 AT with a P2-Phe inhibited thrombin with >150-fold impaired reactivity, however, the defect was restored by either pentasaccharide or by replacing Leu-99 of thrombin with a Gly. Phenylalanine coagulation factor II, thrombin Homo sapiens