Title : Mechanisms of neuroprotective effects of nicotine and acetylcholinesterase inhibitors: role of alpha4 and alpha7 receptors in neuroprotection.

Pub. Date : 2010 Jan

PMID : 19714494






1 Functional Relationships(s)
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1 These results suggest that nicotine as well as AChE inhibitors, donepezil and galantamine, prevent glutamate neurotoxicity through alpha4 and alpha7 nAChRs and the PI3K-Akt pathway. Galantamine acetylcholinesterase Rattus norvegicus