Pub. Date : 2009
PMID : 19710539
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | UCP3 expression in liver modulates gene expression and oxidative metabolism in response to fatty acids, and sensitizes mitochondria to permeability transition. | Fatty Acids | uncoupling protein 3 (mitochondrial, proton carrier) | Mus musculus |
| 2 | CONCLUSION: UCP3 expression in liver exerts direct actions on mitochondrial activity, favoring fatty acid-induced uncoupling and sensitizing mitochondria to permeability transition, as well as causing retrograde signaling to nuclear gene expression consistent with favoring lipid catabolism and oxidative metabolism. | Fatty Acids | uncoupling protein 3 (mitochondrial, proton carrier) | Mus musculus |