Pub. Date : 2009 Nov 6
PMID : 19703466
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | For example, mutant Galpha(i1)-T329A shows an 18-fold increase in basal GDP release rate and, when expressed in culture, it causes a significant decrease in forskolin-stimulated cAMP accumulation. | Guanosine Diphosphate | protein phosphatase 1 regulatory inhibitor subunit 1A | Homo sapiens |
| 2 | The crystal structure of Galpha(i1)-T329A.GDP shows substantial conformational rearrangement of the switch I region and additional striking alterations of side chains lining the catalytic pocket that disrupt the Mg(+2) coordination sphere and dislodge bound Mg(+2). | Guanosine Diphosphate | protein phosphatase 1 regulatory inhibitor subunit 1A | Homo sapiens |