PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 19703466-3 2009 For example, mutant Galpha(i1)-T329A shows an 18-fold increase in basal GDP release rate and, when expressed in culture, it causes a significant decrease in forskolin-stimulated cAMP accumulation. Guanosine Diphosphate 72-75 protein phosphatase 1 regulatory inhibitor subunit 1A Homo sapiens 20-29 19703466-4 2009 The crystal structure of Galpha(i1)-T329A.GDP shows substantial conformational rearrangement of the switch I region and additional striking alterations of side chains lining the catalytic pocket that disrupt the Mg(+2) coordination sphere and dislodge bound Mg(+2). Guanosine Diphosphate 42-45 protein phosphatase 1 regulatory inhibitor subunit 1A Homo sapiens 25-34