Pub. Date : 2009 Sep 1
PMID : 19690197
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | mTOR is a promising therapeutic target both in cisplatin-sensitive and cisplatin-resistant clear cell carcinoma of the ovary. | Cisplatin | mechanistic target of rapamycin kinase | Homo sapiens |
| 2 | mTOR is a promising therapeutic target both in cisplatin-sensitive and cisplatin-resistant clear cell carcinoma of the ovary. | Cisplatin | mechanistic target of rapamycin kinase | Homo sapiens |
| 3 | Increased expression of phospho-mTOR was observed in cisplatin-resistant RMG1-CR and KOC7C-CR cells, compared with the respective parental cells. | Cisplatin | mechanistic target of rapamycin kinase | Homo sapiens |
| 4 | This increased expression of phospho-mTOR in cisplatin-resistant cells was associated with increased activation of AKT. | Cisplatin | mechanistic target of rapamycin kinase | Homo sapiens |
| 5 | Moreover, mTOR inhibition by RAD001 may be efficacious as a second-line treatment of recurrent disease in patients previously treated with cisplatin. | Cisplatin | mechanistic target of rapamycin kinase | Homo sapiens |