Title : Chemoresponsiveness associated with canonical molecular changes in colorectal adenocarcinomas.

Pub. Date : 2009 Aug

PMID : 19661324






1 Functional Relationships(s)
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1 RESULTS: The disease-free survival period (mean+/-SEM) was significantly longer after fluoropyrimidine-based adjuvant chemotherapy in tumors with TGF-beta2 expression (42+/-1.4 vs. 21+/-4.7 months; p=0.005) and D18S46 loss of heterozygosity or microsatellite instability (45.7+/-1.5 vs. 40.5+/-1.4 months; p=0.048). 2-fluoropyrimidine transforming growth factor beta 2 Homo sapiens