Title : Platelet and monocyte antigenic complexes in the pathogenesis of heparin-induced thrombocytopenia (HIT).

Pub. Date : 2009 Jul

PMID : 19630810






3 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 HIT is caused by antibodies that recognize the platelet chemokine, Platelet Factor 4 (PF4), complexed to heparin or to cellular glycosaminoglycans (GAGs). Glycosaminoglycans platelet factor 4 Homo sapiens
2 HIT is caused by antibodies that recognize the platelet chemokine, Platelet Factor 4 (PF4), complexed to heparin or to cellular glycosaminoglycans (GAGs). Glycosaminoglycans platelet factor 4 Homo sapiens
3 We propose that HIT antibodies recognize cell surface PF4/GAG complexes on intravascular cells, including platelets and monocytes that are dynamic and mutable. Glycosaminoglycans platelet factor 4 Homo sapiens