Pub. Date : 2009 Aug 21
PMID : 19627118
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Chiral trans-cyclohexanediamine-benzimidazole organocatalysts promote the conjugate addition of a wide variety of 1,3-dicarbonyl compounds such as malonates, ketoesters, and 1,3-diketones to nitroolefins in the presence of TFA as cocatalyst in toluene as solvent at rt or 0 degrees C. The Michael adducts are obtained in high yield and enantioselectivity, using the chiral 2-aminobenzimidazole 7b as hydrogen-bond-mediated chiral organocatalyst. | 1,3-dicarbonyl compounds | coagulation factor III, tissue factor | Homo sapiens |