Title : Inhibition of ATR protein kinase activity by schisandrin B in DNA damage response.

Pub. Date : 2009 Sep

PMID : 19625493






1 Functional Relationships(s)
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1 The protein kinase activity of immunoaffinity-purified ATR was dose-dependently decreased by SchB in vitro (IC(50): 7.25 muM), but the inhibitory effect was not observed in ATM, Chk1, PI3K, DNA-PK, and mTOR. schizandrin B mechanistic target of rapamycin kinase Homo sapiens