Title : Negative regulation of Hedgehog signaling by liver X receptors.

Pub. Date : 2009 Oct

PMID : 19608643






2 Functional Relationships(s)
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Protein Name
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1 Activation of LXR by specific pharmacological ligands, TO901317 and GW3965, inhibited the responses of pluripotent bone marrow stromal cells and calvaria organ cultures to sonic Hh, resulting in the inhibition of expression of Hh-target genes, Gli1 and Patched1, and Gli-dependent transcriptional activity. T0901317 GLI family zinc finger 1 Homo sapiens
2 Activation of LXR by specific pharmacological ligands, TO901317 and GW3965, inhibited the responses of pluripotent bone marrow stromal cells and calvaria organ cultures to sonic Hh, resulting in the inhibition of expression of Hh-target genes, Gli1 and Patched1, and Gli-dependent transcriptional activity. T0901317 GLI family zinc finger 1 Homo sapiens