Title : Carbodiimide EDC induces cross-links that stabilize RNase A C-dimer against dissociation: EDC adducts can affect protein net charge, conformation, and activity.

Pub. Date : 2009 Aug 19

PMID : 19606852






1 Functional Relationships(s)
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1 Here, a widely used conjugating agent, 1-ethyl-3-(3-dimethylaminoisopropyl) carbodiimide (EDC), has been used to induce the formation of amide bonds between carboxylate and amine groups of different subunits of the RNase A C-dimer. Amides ribonuclease A family member 1, pancreatic Homo sapiens