Title : ABCB1 and cytochrome P450 polymorphisms: clinical pharmacogenetics of clozapine.

Pub. Date : 2009 Aug

PMID : 19593168






1 Functional Relationships(s)
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1 In patients comedicated with fluvoxamine, a strong CYP1A2 inhibitor, clozapine and norclozapine concentrations correlate with CYP3A activity (r = 0.44, P = 0.075; r = 0.63, P = 0.007, respectively). Fluvoxamine cytochrome P450 family 3 subfamily A member 4 Homo sapiens