Title : Insights into the substrate specificity, inhibitors, regulation, and polymorphisms and the clinical impact of human cytochrome P450 1A2.

Pub. Date : 2009 Sep

PMID : 19590965






1 Functional Relationships(s)
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Protein Name
Organism
1 Human CYP1A2 is one of the major CYPs in human liver and metabolizes a variety of clinically important drugs (e.g., clozapine, tacrine, tizanidine, and theophylline), a number of procarcinogens (e.g. benzo[a]pyrene and aflatoxin B(1)), and several important endogenous compounds (e.g. steroids and arachidonic acids). Benzo(a)pyrene cytochrome P450 family 1 subfamily A member 2 Homo sapiens