Title : Omega-3 fatty acids regulate gene expression levels differently in subjects carrying the PPARalpha L162V polymorphism.

Pub. Date : 2009 Sep

PMID : 19585164






5 Functional Relationships(s)
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1 Data demonstrates that gene expression levels of PPARalpha and apolipoprotein AI (APOA1) were significantly lower for carriers of the PPARalpha-V162 allele compared to L162 homozygotes after the addition of DHA and a mixture of EPA:DHA. Docosahexaenoic Acids peroxisome proliferator activated receptor alpha Homo sapiens
2 Data demonstrates that gene expression levels of PPARalpha and apolipoprotein AI (APOA1) were significantly lower for carriers of the PPARalpha-V162 allele compared to L162 homozygotes after the addition of DHA and a mixture of EPA:DHA. Docosahexaenoic Acids peroxisome proliferator activated receptor alpha Homo sapiens
3 Data demonstrates that gene expression levels of PPARalpha and apolipoprotein AI (APOA1) were significantly lower for carriers of the PPARalpha-V162 allele compared to L162 homozygotes after the addition of DHA and a mixture of EPA:DHA. Docosahexaenoic Acids peroxisome proliferator activated receptor alpha Homo sapiens
4 Data demonstrates that gene expression levels of PPARalpha and apolipoprotein AI (APOA1) were significantly lower for carriers of the PPARalpha-V162 allele compared to L162 homozygotes after the addition of DHA and a mixture of EPA:DHA. Docosahexaenoic Acids peroxisome proliferator activated receptor alpha Homo sapiens
5 Additionally, lipoprotein lipase (LPL) gene expression displayed a tendency to be lower in the PPARalpha L162V polymorphism subgroup after the addition of a mixture of EPA:DHA. Docosahexaenoic Acids peroxisome proliferator activated receptor alpha Homo sapiens