Title : Swertiamarin: a lead from Enicostemma littorale Blume. for anti-hyperlipidaemic effect.

Pub. Date : 2009 Sep 1

PMID : 19577561






3 Functional Relationships(s)
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1 The 3-hydroxy 3-methyl glutaryl Co A (HMG-Co A) reductase activity was significantly inhibited in swertiamarin and atorvastatin treated groups compared to high cholesterol fed control group. swertiamarin 3-hydroxy-3-methylglutaryl-CoA reductase Rattus norvegicus
2 In conclusion our data suggest that swertiamarin possess high antiatherogenic potential and an effective cholesterol lowering agent and inhibition of HMG-Co A reductase may be one of the main mechanisms of hypolipidemic effect of swertiamarin. swertiamarin 3-hydroxy-3-methylglutaryl-CoA reductase Rattus norvegicus
3 In conclusion our data suggest that swertiamarin possess high antiatherogenic potential and an effective cholesterol lowering agent and inhibition of HMG-Co A reductase may be one of the main mechanisms of hypolipidemic effect of swertiamarin. swertiamarin 3-hydroxy-3-methylglutaryl-CoA reductase Rattus norvegicus