Title : Stimulated stromal cells induce gamma-globin gene expression in erythroid cells via nitric oxide production.

Pub. Date : 2009 Oct

PMID : 19576950






1 Functional Relationships(s)
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1 OBJECTIVE: We have previously shown that nitric oxide (NO) is involved in the hydroxyurea-induced increase of gamma-globin gene expression in cultured human erythroid progenitor cells and that hydroxyurea increases NO production in endothelial cells via endothelial NO synthase (NOS). Hydroxyurea nitric oxide synthase 2 Homo sapiens