Title : RASSF1A expression inhibits cell growth and enhances cell chemosensitivity to mitomycin in BEL-7402 hepatocellular carcinoma cells.

Pub. Date : 2009 Jun 5

PMID : 19567146






4 Functional Relationships(s)
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Protein Name
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1 RASSF1A expression inhibits cell growth and enhances cell chemosensitivity to mitomycin in BEL-7402 hepatocellular carcinoma cells. Mitomycin Ras association domain family member 1 Homo sapiens
2 Re-expression of wild-type RASSF1A could enhance the inhibition of cell proliferation and the percentage of apoptotic cells following cell treatment with mitomycin, but had no significant effect when combined with adriamycin, etoposide, 5-fluorouracil and cisplatin treatment. Mitomycin Ras association domain family member 1 Homo sapiens
3 CONCLUSION: Wild-type RASSF1A inhibits cell growth and enhances cell chemosensitivity to mitomycin in hepatocellular carcinoma, suggesting that RASSF1A may serve as a new target for gene therapy in hepatocellular carcinoma patients. Mitomycin Ras association domain family member 1 Homo sapiens
4 CONCLUSION: Wild-type RASSF1A inhibits cell growth and enhances cell chemosensitivity to mitomycin in hepatocellular carcinoma, suggesting that RASSF1A may serve as a new target for gene therapy in hepatocellular carcinoma patients. Mitomycin Ras association domain family member 1 Homo sapiens