Title : The association of XRCC1 gene single nucleotide polymorphisms with response to neoadjuvant chemotherapy in locally advanced cervical carcinoma.

Pub. Date : 2009 Jun 29

PMID : 19563645






4 Functional Relationships(s)
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1 The aim of our study was to investigate the association between XRCC1 gene single nucleotide polymorphisms (SNPs) and NAC response. nac X-ray repair cross complementing 1 Homo sapiens
2 The association of XRCC1 gene SNPs and protein expression with NAC response were analyzed. nac X-ray repair cross complementing 1 Homo sapiens
3 The expression level of XRCC1 protein was significantly associated with response to NAC. nac X-ray repair cross complementing 1 Homo sapiens
4 CONCLUSION: SNP of XRCC1 gene at codon 399 influences the response of cervical carcinoma to platinum-based NAC. nac X-ray repair cross complementing 1 Homo sapiens