Title : Celecoxib enhanced the sensitivity of cancer cells to anticancer drugs by inhibition of the expression of P-glycoprotein through a COX-2-independent manner.

Pub. Date : 2009 Sep 1

PMID : 19562670






2 Functional Relationships(s)
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Protein Name
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1 Celecoxib enhanced the sensitivity of cancer cells to anticancer drugs by inhibition of the expression of P-glycoprotein through a COX-2-independent manner. Celecoxib ATP binding cassette subfamily B member 1 Homo sapiens
2 Enzyme activity and methylation analyses demonstrated that the inhibitory effect of celecoxib on p170 was independent on COX-2 but closely related to hypermethylation of MDR1 gene promoter. Celecoxib ATP binding cassette subfamily B member 1 Homo sapiens