Pub. Date : 2009 Oct
PMID : 19560877
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Is it the time for metformin to take place in adjuvant treatment of Her-2 positive breast cancer? | Metformin | erb-b2 receptor tyrosine kinase 2 | Homo sapiens |
| 2 | Metformin causes Her-2 suppression via the inhibition of mTOR in breast cancer cells. | Metformin | erb-b2 receptor tyrosine kinase 2 | Homo sapiens |
| 3 | Thus, we believe that the time has arrived both to target insulin reduction and to alter Her-2 oncogene based molecular pathogenetic steps in breast cancer by using metformin as an adjuvant therapy in breast cancer patients. | Metformin | erb-b2 receptor tyrosine kinase 2 | Homo sapiens |