Pub. Date : 2011 Jun
PMID : 19560233
8 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | HFE polymorphisms affect cellular glutamate regulation. | Glutamic Acid | homeostatic iron regulator | Homo sapiens |
| 2 | In support of this hypothesis, expression of H63D HFE is associated with increased calcium-induced glutamate secretion and decreased cellular glutamate uptake. | Glutamic Acid | homeostatic iron regulator | Homo sapiens |
| 3 | In support of this hypothesis, expression of H63D HFE is associated with increased calcium-induced glutamate secretion and decreased cellular glutamate uptake. | Glutamic Acid | homeostatic iron regulator | Homo sapiens |
| 4 | HFE-dependent effects on glutamate uptake were confirmed in astrocytoma cell lines with endogenous expression of HFE. | Glutamic Acid | homeostatic iron regulator | Homo sapiens |
| 5 | HFE-dependent effects on glutamate uptake were confirmed in astrocytoma cell lines with endogenous expression of HFE. | Glutamic Acid | homeostatic iron regulator | Homo sapiens |
| 6 | The ability of minocycline and the antioxidant Trolox to increase glutamate uptake differed by HFE genotype and implicate oxidative stress in glutamate regulation. | Glutamic Acid | homeostatic iron regulator | Homo sapiens |
| 7 | This study demonstrates HFE cellular effects that extend beyond iron regulation, and suggests that H63D HFE may promote glutamate toxicity. | Glutamic Acid | homeostatic iron regulator | Homo sapiens |
| 8 | This study demonstrates HFE cellular effects that extend beyond iron regulation, and suggests that H63D HFE may promote glutamate toxicity. | Glutamic Acid | homeostatic iron regulator | Homo sapiens |