Pub. Date : 2009 Aug
PMID : 19557000
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | We show the induction of DSBs and DDR activation in post-mitotic primary neurons and lymphocytes treated with camptothecin, with the induction of nuclear DDR foci containing activated ATM, gamma-H2AX (phosphorylated histone H2AX), activated CHK2 (checkpoint kinase 2), MDC1 (mediator of DNA damage checkpoint 1) and 53BP1 (p53 binding protein 1). | Camptothecin | tumor protein p53 binding protein 1 | Homo sapiens |
2 | We show the induction of DSBs and DDR activation in post-mitotic primary neurons and lymphocytes treated with camptothecin, with the induction of nuclear DDR foci containing activated ATM, gamma-H2AX (phosphorylated histone H2AX), activated CHK2 (checkpoint kinase 2), MDC1 (mediator of DNA damage checkpoint 1) and 53BP1 (p53 binding protein 1). | Camptothecin | tumor protein p53 binding protein 1 | Homo sapiens |