Title : In vivo and in vitro effects of fluoroquinolones on lipopolysaccharide-induced pro-inflammatory cytokine production.

Pub. Date : 2009 Jun

PMID : 19554401






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 In LPS-treated mice, ciprofloxacin, gatifloxacin, and norfloxacin (100 mg/kg) significantly reduced the serum TNF-alpha level (6.8%-63.6% of control). Norfloxacin tumor necrosis factor Mus musculus
2 Ciprofloxacin, gatifloxacin, and norfloxacin (100 mug/ml) inhibited both TNF-alpha (12.1%-69.0% of control) and IL-1beta production (22.1%-68.8% of control). Norfloxacin tumor necrosis factor Mus musculus