Pub. Date : 2009 Sep
PMID : 19553242
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | In fibroblasts from affected subjects, oxysterol stimulation resulted in increased ABCA1 protein expression and normalized their defective phospholipid efflux defect. | Oxysterols | ATP binding cassette subfamily A member 1 | Homo sapiens |
| 2 | The defect in phospholipid efflux is due to defective ABCA1 protein regulation and can be corrected by treatment with physiological oxysterols, a current therapeutic target of interest, that may, with further studies, be used to raise HDL levels in patients with severe HDL deficiencies. | Oxysterols | ATP binding cassette subfamily A member 1 | Homo sapiens |