Pub. Date : 2009 Aug
PMID : 19549761
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Expression of Bcl-2 and caspase-3 activation increased in B cells treated with 10 mumol/L resveratrol compared with mitogen alone (P < 0.01), and trends for dose-responsive increases in Bcl-2 expression and caspase-3 activation were observed (P-trend < 0.0001). | Resveratrol | BCL2 apoptosis regulator | Homo sapiens |
2 | Expression of Bcl-2 and caspase-3 activation increased in B cells treated with 10 mumol/L resveratrol compared with mitogen alone (P < 0.01), and trends for dose-responsive increases in Bcl-2 expression and caspase-3 activation were observed (P-trend < 0.0001). | Resveratrol | BCL2 apoptosis regulator | Homo sapiens |
3 | These data show that human B lymphocyte proliferation and apoptosis are modified by physiological concentrations of resveratrol and suggest that exposure of human B cells to resveratrol may increase survival by upregulating Bcl-2. | Resveratrol | BCL2 apoptosis regulator | Homo sapiens |