Title : Intraneuronal pyroglutamate-Abeta 3-42 triggers neurodegeneration and lethal neurological deficits in a transgenic mouse model.

Pub. Date : 2009 Oct

PMID : 19547991






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 N-terminally truncated and pyroglutamate modified Abeta starting at position 3 and ending with amino acid 42 [Abeta(3(pE)-42)] have been previously shown to represent a major species in the brain of AD patients. Pyrrolidonecarboxylic Acid histocompatibility 2, P region beta locus Mus musculus