Title : Pyrimidinyl-arylpropionic acid derivatives: viable resources in the development of new antineoplastic agents.

Pub. Date : 2010 Aug

PMID : 19533021






1 Functional Relationships(s)
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1 MTT assay results revealed that several compounds were able to inhibit cell proliferation in a dose-dependent manner with IC(50) 12.7-29.7 microM, better than that of rosiglitazone (45.9-141 microM), although the PPARgamma agonistic activity of most compounds is much lower than rosiglitazone. monooxyethylene trimethylolpropane tristearate peroxisome proliferator activated receptor gamma Homo sapiens