Title : Thiacremonone augments chemotherapeutic agent-induced growth inhibition in human colon cancer cells through inactivation of nuclear factor-{kappa}B.

Pub. Date : 2009 Jun

PMID : 19531569






2 Functional Relationships(s)
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1 Oral treatment of mice with thiacremonone (1 mg/kg) by administering it in drinking water for 4 weeks significantly augmented docetaxel (1 mg/kg, i.p., four times)-induced decrease of tumor growth accompanied with regulation of NF-kappaB activity and NF-kappaB target genes. Docetaxel nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus
2 Oral treatment of mice with thiacremonone (1 mg/kg) by administering it in drinking water for 4 weeks significantly augmented docetaxel (1 mg/kg, i.p., four times)-induced decrease of tumor growth accompanied with regulation of NF-kappaB activity and NF-kappaB target genes. Docetaxel nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus