Pub. Date : 2009 Apr
PMID : 19526759
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | in vivo studies showed that icariin at the dose of 20 mg/kg significantly lowered serum TNF-alpha and IL-6 levels (P < 0.01), reduced the average fluorescence intensity of adhesion molecules CD11b (P < 0.01), and alleviated pulmonary inflammatory cell infiltration. | icariin | tumor necrosis factor | Mus musculus |
| 2 | CONCLUSION: Icariin is a safe and effective natural anti-inflammatory drug, its partial mechanism is possible the multiple links intervention on pro-inflammatory cytokines (TNF-alpha, IL-6), inflammatory mediators (NO) and adhesion molecules (CD11b). | icariin | tumor necrosis factor | Mus musculus |