Title : Ovariectomy and estrogen treatment modulate iron metabolism in rat adipose tissue.

Pub. Date : 2009 Oct 15

PMID : 19501056






3 Functional Relationships(s)
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Protein Name
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1 At cellular level, the maintenance of iron homeostasis is largely accomplished by the transferrin receptor (TfR-1) and by ferritin, whose expression is mainly regulated post-transcriptionally by iron regulatory proteins (IRPs). Iron transferrin receptor Rattus norvegicus
2 At cellular level, the maintenance of iron homeostasis is largely accomplished by the transferrin receptor (TfR-1) and by ferritin, whose expression is mainly regulated post-transcriptionally by iron regulatory proteins (IRPs). Iron transferrin receptor Rattus norvegicus
3 Our results indicate that estrogen level changes can regulate the binding activity of the IRP1, and consequently ferritin and TfR-1 expression in adipose tissue, suggesting a relationship among serum and tissue iron parameters, estrogen status and adiposity. Iron transferrin receptor Rattus norvegicus