Title : Excitotoxic-mediated transcriptional decreases in HCN2 channel function increase network excitability in CA1.

Pub. Date : 2009 Sep

PMID : 19500574






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Lamotrigine, known to increase Ih, reversed the impact of KA on burst duration in CA1 at both time-points linking a transcriptional reduction in HCN2 function to increased burst duration. Lamotrigine carbonic anhydrase 1 Homo sapiens