Pub. Date : 2009 Aug
PMID : 19499404
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | The present study was conducted to elucidate whether progesterone affects IGF-I mRNA through progesterone receptor B(PRB) mRNA in leiomyoma. | Progesterone | RB transcriptional corepressor 1 | Homo sapiens |
2 | CONCLUSION: The progesterone may down-regulate IGF-I expression through PRB, and PRA appears to inhibit this function of progesterone by inhibiting the transcription of PRB; thus, the action of progesterone on leiomyoma growth may depend on different ratios of PRA and PRB. | Progesterone | RB transcriptional corepressor 1 | Homo sapiens |