Title : Cross-regulation between colocalized nicotinic acetylcholine and 5-HT3 serotonin receptors on presynaptic nerve terminals.

Pub. Date : 2009 Jun

PMID : 19498419






1 Functional Relationships(s)
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1 RESULTS: Application of 500 nmol/L nicotine following sustained stimulation with the highly selective 5-HT(3) receptor agonist m-chlorophenylbiguanide at 100 nmol/L resulted in markedly reduced Ca(2+) responses (28% of control) in only those striatal nerve endings that originally responded to m-chlorophenylbiguanide. Nicotine 5-hydroxytryptamine receptor 3A Rattus norvegicus